厦门大学临床医学系导师:李炜

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厦门大学临床医学系导师:李炜

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厦门大学临床医学系导师:李炜 正文

       姓名:李炜  
   性别:男  
   职称:教授
   所获学位:硕士
   授予单位:同济医科大学 
   学院:医学院
   研究方向:角膜上皮干细胞,角膜组织工程,眼表与角膜疾病发病机理
   学科专长:眼表疾病与角膜病
   邮箱:wei1018@gmail.com
   通信地址:厦门翔安南路
   邮编:361102
  
  个人中文简介
  李炜,厦门大学眼科研究所、厦门大学附属厦门眼科中心、福建省眼科与视觉科学重点实验室教授,博士生导师。中华眼科学会角膜病学组委员,中华眼科杂志通讯编委,中华细胞与干细胞移植杂志编委,亚洲角膜病学会会员,美国视觉与眼科研究学会会员,美国眼科学会会员,国际眼表疾病学会会员。1994年毕业于皖南医学院,获医学学士学位,1999年毕业于同济医科大学(现华中科技大学同济医学院),获眼科学硕士学位。2003年5月至2007年1月在美国迈阿密 Ocular Surface Center 从事博士后研究工作,并担任生物技术公司TissueTech Inc.研究与发展部的研究科学家。近五年来,在眼科学、病理学、细胞生物学等多学科领域SCI收录期刊上发表论文30余篇,其中第一作者9篇,通讯作者5篇,研究成果申请了6项美国专利。目前主要从事角膜上皮干细胞增殖与分化的基因调控,角膜上皮干细胞移植,眼表面重建,以及角膜组织工程方面的研究。承担1项国家重大科学研究计划项目子课题,1 项国家重大科学仪器设备开发项目子课题,3项国家自然科学基金面上项目,1项福建省杰出青年基金项目,1项人事部留学人员科技项目,参与6项国家及省部级科研项目。2011年入选福建省新世纪优秀人才,2012年被确认为厦门市引进的重点人才。
  
  个人英文简介
  Dr. Wei Li graduated from Wannan Medical College in 1994, and got his Master’s degree from Tongji Medical University in 1999. After that, he had been worked as a chief ophthalmologist in Shenzhen for 4 years. From May 2003 to Feb 2007, he had been trained in Ocular Surface Center (Miami, Florida, USA) under the guidance of Dr. Scheffer C G Tseng. During his post-doctoral fellowship, he conducted basic research on corneal limbal stem cell, amniotic membrane, and corneal tissue engineering. In March 2007, he joined
  Xiamen University Medical College, and worked as associate professor, and then professor of Ophthalmology till now in the Eye Institute of Xiamen University. He also works as a cornea and ocular surface disease specialist in Xiamen Eye Center.
  Dr. Li has published more than 30 papers on peer-reviewed journals such as IOVS, JPathol, Cell Res, J Biol Chem, J Cell Physiol, Stem Cells, Am J Physiol, and Exp Eye Res,
and so on. He also contributed to chapters of four scientific books published in China or United States. Eight US or Chinese patents have been filed based on his research findings.He has obtained several awards from municipal and provincial government, including Prize for Progress in Science and Technology, and Yunsheng Youth Science andTechnology Prize.
  Dr. Li continuously focuses his basic research on corneal limbal stem cell and cornealtissue engineering, and clinic research on ocular surface reconstruction, as well as the treatment of severe ocular surface and corneal diseases. His research projects were supported by the National Natural Science Foundation of China, the Natural Science
Foundation of Fujian province, and the Ministry of Human Resources and Social Security of China.
  Dr. Li is now active member of several academic societies such as Chinese Medical
Association (CMA), Asian Cornea Society (ACS), Association for Research in Vision and Ophthalmology (ARVO), International Ocular Surface Society (IOSS), American Academy of Ophthalmology (AAO), and American Physiology Society (APS). He is committee member of Chinese Cornea Society, communication editor of Chinese Journal of Ophthalmology, editor of Chinese Journal of Cell Transplantation & Stem Cell Transplantation, reviewer of National Natural Science Foundation of China, and reviewer of several international journals.
  
  代表性成果
  论文发表

  (1) A Novel Method for Preservation of Human Corneal Limbal Tissue,Invest Ophthalmol Vis Sci.,2013年06月
  (2) Increased importin 13 activity is associated with the pathogenesis of pterygium,Molecular Vision,2013年03月
  (3) Activation of Smad-Mediated TGF-b Signaling Triggers Epithelial–Mesenchymal Transitions in Murine Cloned Corneal Progenitor Cells ,J. Cell. Physiol.,2013年02月
  (4) Strategies of human corneal endothelial tissue regeneration,Regen. Med.,2013年02月
  (5) Activation of Smad-mediated TGF-β signaling triggers epithelial-mesenchymal transitions in murine cloned corneal progenitor cells. ,J Cell Physiol.,2012年06月
  (6) Porcine Corneal Equivalent for Xenographs,Science Supplement,2012年04月
  (7) Netrin-1 Simultaneously Suppresses Corneal Inflammation and Neovascularization.,Invest Ophthalmol Vis Sci. ,2012年03月
  (8) Oxygen tension affects terminal differentiation of corneal limbal epithelial cells.,J Cell Physiol.,2011年09月
  (9) Amniotic Membrane Inhibits Squamous Metaplasia of Human Conjunctival Epithelium,Am J Physiol Cell Physiol,2011年07月
  (10) Changes in corneal epithelial layer inflammatory cells in aqueous tear-deficient dry eye. ,Invest Ophthalmol Vis Sci. ,2010年01月
  (11) Biochemical Characterization and Function of Complexes Formed by Hyaluronan and the Heavy Chains of Inter-{alpha}-Inhibitor (HC*HA) Purified from Extracts of Human Amniotic Membrane. ,J Biol Chem. ,2009年06月
  (12) Abnormal Epithelial Differentiation and Tear Film Alteration in Pinguecula.,Invest Ophthalmol Vis Sci.,2009年01月
  (13) Suppression of activation and induction of apoptosis in RAW264.7 cells by amniotic membrane extract,Invest Ophthalmol Vis Sci. ,2008年10月
  (14) Reversal of myofibroblasts by amniotic membrane stromal extract.,J Cell Physiol,2008年07月
  (15) Down-regulation of Pax6 is associated with abnormal differentiation of corneal epithelial cells in severe ocular surface diseases ,J Pathol,2008年01月
  (16) Air exposure induced squamous metaplasia of human limbal epithelium,Invest Ophthalmol Vis Sci,2008年01月
  (17) Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells,Stem Cells,2007年08月
  (18) A novel method of isolation, preservation, and expansion of human corneal endothelial cells.,Invest Ophthalmol Vis Sci,2007年02月
  (19) The fate of limbal epithelial progenitor cells during explant culture on intact amniotic membrane.,Invest Ophthalmol Vis Sci,2007年02月
  (20) Niche regulation of corneal epithelial stem cells at the limbus.,Cell Res,2007年01月
  
  专著发表:
  (1) 眼科学基础,人民卫生出版社,2011年08月,教材
  (2) 临床解剖学(眼科学分册),山东科技出版社,2009年10月,编著
  (3) 眼睑外科手术图解,山东科学技术出版社,2008年10月,译著
  
  获奖、专利和发明:
  (1) 一种体外干眼模型的建立方法 ,发明专利,2011年08月,国家知识产权局,等级:1
  (2) 中华医学科技奖,其他科研奖,2010年12月,中华医学会,等级:3
  (3) 厦门市科技进步奖,其他科研奖,2009年11月,厦门市政府,厦门市科技局,等级:1
  (4) 福建省科技进步奖,省部级科研奖,2010年12月,福建省人民政府,等级:1
  (5) 运盛青年科技奖,其他科研奖,2011年08月,福建省运盛基金会,等级:1
  
  如果发现导师信息存在错误或者偏差,欢迎随时与我们联系,以便进行更新完善。
  

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