湘潭大学化学学院导师：张雪飞 正文

[导师姓名]
张雪飞

[所属院校]
湘潭大学

[基本信息]
导师姓名：张雪飞
性别：男
人气指数：1311
所属院校：湘潭大学
所属院系：化学学院
职称：教授
导师类型：博导
招生专业：

[通讯方式]
电子邮件：zxf7515@163.com

[个人简述]
毕业于中国科学院长春应用化学所，一直从事生物医用可降解高分子材料合成及应用的研究工作。先后在《Biomaterials》、《Journal of Controlled Release》、《Biomacromolecules》等国际期刊发表相关SCI收录论文20多篇，参编专著一部，申请中国专利11项，已授权6项。自2005年以来，主持的科研项目共有9项，国家级4项，省级4项，校级2项。目前在研国家自然科学基金2项：基于多药协同作用和逆转肿瘤耐药性的纳米药物载体的设计和构筑（国家自然科学基金面上项目）；具有靶向和量子点示踪功能的水溶性聚酯高分子键合药研究（国家自然科学基金面上项目）。

[科研工作]
论文专著1. (Methoxy-Poly(ethylene glycol)-block-Poly(ε-caprolactone) Bearing Pendant Aldehyde Groups as pH-Responsive Drug Delivery Carrier). Australian Journal of Chemistry 2013, 66(12), 1576-1583. Gejun Ma, Deshan Li, Ji Wang,*Xuefei Zhang, *Haoyu Tang2. pH-Triggered Charge-Reversal Polypeptide Nanoparticles for Cisplatin Delivery: Preparation and In Vitro Evaluation. BIOMACROMOLECULES, 2013,14(6), 2023-2032, Huang Yue, *Tang, Zhaohui, *Zhang, Xuefei, Yu Haiyang, Sun Hai, Pang Xuan, Chen Xuesi3. Synthesis and characterization of a novel biodegradable amphiphilic MPEG-dendritic block copolymer containing (glycolic acid)-alt-(lactic acid) oligomer and glycerol. Journal of Controlled Release, 2011,152: e264-e266. Jianwei Jiang, Li Zhang, Miao Wu, Xuefei Zhang*4. Synthesis and Characterization of a Well-Defined Amphiphilic Block Copolymer and Its Paclitaxel Prodrug from Methoxy Poly(ethylene glycol) and Oligomer of Glycolic Acid. Journal of Applied Polymer Science, 2011, 758-766. Li Zhang, Jinyan Fu, Zhixiang Xia, Ping Wu, Xuefei Zhang*5. Synthesis and Characterization of a Novel Biodegradable Amphiphilic Dendritic Polyether-ester. Australian Journal of Chemistry. 2012, 65, 545–551, Jin peng Xiao, Hong Wang, Qiang Yi, Gejun Ma, Xue fei Zhang*6. A new approach for synthesis of the comb-shaped poly (e-caprolactone) brushes on the surface of nano-hydroxyapatite by combination of ATRP and ROP, Journal of Colloid and Interface Science, 2010, 352: 36-42. Liang Zeng, Haibo Wang, Guoxin Fu , Jianwei Jiang, Xuefei Zhang*7. Fabrication and characterization of nanocomposites with high-impact polystyrene and hydroxyapatite with well-defined polystyrene via ATRP. Journal of Reinforced Plastics and Composites , 2011, 30 , 1445-1453. Guoxin Fu, Zhixiang Xia, Jianwei Jiang, Bo Jing, Xuefei Zhang *8. Preparation and Characterization of Nanocomposites based on Poly (ε-caprolactone) and the Surface Grafted Nanohydroxyapatite with the Comb-shaped Poly (ε-caprolactone) Brushes, Polymers and Polymer Composites, 2012, 20,463-469 . Guoxin Fu, Liang Zeng, Jianwei Jiang, Zhixiang Xia, Bo Jing, Xuefei Zhang *9. A novel amphotropic polymer based on cellulose nanocrystals grafted with azo polymers, European Polymer Journal, 2008, 44, 2830–2837. Qunxing Xu , Jie Yi , Xuefei Zhang , Hailiang Zhang,10. Chiral-nematic self-ordering of rodlike cellulose nanocrystals grafted with poly(styrene) in both thermotropic and lyotropic states, Polymer, 2008, 49, 4406–4412. Jie Yi, Qunxing Xu , Xuefei Zhang, Hailiang Zhang.11. Design, Synthesis, and Characterization of a Combined Main-Chain/Side-Chain Liquid Crystalline Polymer Based on Mesogen-Jacketed Liquid Crystal Polymer via Atom Transfer Radical Polymerization ,Journal of Polymer Science: Part A: Polymer Chemistry, 2008, 46, 7310–7320. Helou Xie, Tianhui Hu, Xuefei Zhang, Hailiang Zhang, Erqiang Chen, Qifeng Zhou.12. Synthesis and Characterization of a Novel Diblock Copolymer with a Polyrotoxane Block, Polymer Bulletin, 2008,61 , 53–62. Bin Ni, Xingzhu Wang, Huaguang Yu, Xuefei Zhang, Hailiang Zhang, Wai-Yeung Wong.13. Synthesis of Poly (ethylene oxide)-b-polystyrene-bpoly(4-vinylpyridine) ABC Triblock Copolymers by Two-step Atom Transfer Radical Polymerization, Iranian Polymer Journal, 2008,17, 781-790. Qizhen Xiao, Xuefei Zhang, Jie Yi, Xingzhu Wang, Hailiang Zhang.14. Temperature-induced chiral nematic phase changes of suspensions of poly(N,N-dimethylaminoethyl methacrylate)-grafted cellulose nanocrystals. Cellulose, 2009, 16, 989–997. Jie Yi, Qunxing Xu, Xuefei Zhang, Hailiang Zhang.15. Comparative study of paclitaxel physically encapsulated in and chemically conjugated with PEG-PLA. Polym. Adv. Technol. 2009, 20, 843–848. Xiaoyi Xu, Xuefei Zhang, Xiuhong Wang, Yuxin Li, Xiabin Jing.16. Synthesis and characterization of the paclitaxel/MPEG-PLA block copolymer conjugate, Biomaterials，2005 26: 2121－2128. Xuefei Zhang, Yuxin Li, Xuesi Chen, Xiuhong Wang, Xiaoyi Xu, Qizhi Liang, Junli Hu, Xiabin Jing.17. 载有胰岛素的可生物降解微球的制备与表征，高等学校化学学报，200526: 554-557. 张雪飞, 胡俊丽, 陈学思, 景遐斌。18. Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation，Journal of Controlled Release, 2005 105: 43-51. Jing Zeng, Lixin Yang, Qizhi Liang, Xuefei Zhang, Huili Guan, Xiuling Xu, Xuesi Chen and Xiabin Jing.19. Synthesis of a novel structural triblock copolymer of poly(γ -benzyl--glutamic acid)-b-poly(ethylene oxide)-b-poly(-caprolactone)， Biomaterials，2004 25: 3553-3558. Mingxiao Deng, Rong Wang, Guangzhuo Rong , Jingru Sun , Xuefei Zhang, Xuesi Chen and Xiabin Jing.20. Stereoselective Polymerization of rac-Lactide Using a Monoethylaluminum Schiff Base Complex，Biomacromolecules, 2004 5: 965-970. Tang, Z. Chen, X. Pang, X. Yang, Y. Zhang, X. Jing, X.21. Stereoselective polymerization of rac-lactide with a bulky aluminum/Schiff base complex，Journal of Polymer Science Part A: Polymer Chemistry 2004 42: 5974-5982. Zhaohui Tang, Xuesi Chen, Yongkun Yang, Xuan Pang, Jingru Sun, Xuefei Zhang, Xiabin Jing.22. Synthesis of four-armed poly(-caprolactone)-block-poly(ethylene oxide) by diethylzinc catalyst，Journal of Polymer Science Part A: Polymer Chemistry 2004 42: 950-959. Mingxiao Deng, Xuesi Chen, Longhai Piao, Xuefei Zhang, Zhongli Dai, Xiabin Jing.Probing the micellization of diblock and triblock copolymers of poly(l-lactide) and poly(ethylene glycol) in aqueous and NaCl salt solutions Colloid & Polymer Science 2004 282: 343 – 350. Zhongli Dai, Longhai Piao, Xuefei Zhang, Mingxiao Deng, Xuesi Chen and Xiabin Jin.

[教育背景]
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湘潭大学

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